7/21—Household transmission of SARS-CoV-2
Household transmission of SARS-CoV-2
The infection rate of close contacts was 38% for households with 1 contact, 50% for households with 2 contacts, and 31% for households with 3 contacts.
Discontinuation of Isolation for Persons with COVID-19 Not in Healthcare Settings
The US CDC no longer recommends testing to determine when to discontinue home isolation, except in certain circumstances. Persons with COVID-19 who have symptoms and were directed to care for themselves at home may discontinue isolation under the following conditions:
At least 10 days have passed since symptom onset and
At least 24 hours have passed since resolution of fever without the use of fever-reducing medications and
Other symptoms have improved.
Testing of asymptomatic individuals for fast feedback-control of COVID-19 pandemics
We argue that frequent sampling of the fraction of a priori non-symptomatic but infectious humans (either by random or cohort testing) significantly improves the management of the COVID-19 pandemic, when compared to intervention strategies relying on data from symptomatic cases only. This is because such sampling measures the incidence of the disease, the key variable controlled by restrictive measures
All-cause excess mortality observed by age group and regions in the first wave of the COVID-19 pandemic in England
The excess [mortality] observed during the pandemic was higher than excesses noted in the past 5 years. It concerned all regions and all age groups, except the 0–14 year olds, but was more pronounced in the London region and in those aged ≥ 85 years.
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