Effectiveness Moderna vaccine vs. Delta, Mu, and other emerging variants
covid1.substack.com
Effectiveness of mRNA-1273 against Delta, Mu, and other emerging variants [Preprint.] The study included 8,153 cases and their matched controls. Two-dose VE (95% confidence interval) was 86.7% (84.3-88.7%) against Delta infection, 98.4% (96.9-99.1%) against Alpha, 90.4% (73.9-96.5%) against Mu, 96-98% against other identified variants, and 79.9% (76.9-82.5%) against unidentified variants. VE against Delta declined from 94.1% (90.5-96.3%) 14-60 days after vaccination to 80.0% (70.2-86.6%) 151-180 days after vaccination. Waning was less pronounced for non-Delta variants. VE against Delta hospitalization was 97.6% (92.8-99.2%). Two doses of mRNA-1273 were highly effective against all SARS-CoV-2 variants. However, VE against Delta moderately declined with increasing time since vaccination.
Effectiveness Moderna vaccine vs. Delta, Mu, and other emerging variants
Effectiveness Moderna vaccine vs. Delta, Mu…
Effectiveness Moderna vaccine vs. Delta, Mu, and other emerging variants
Effectiveness of mRNA-1273 against Delta, Mu, and other emerging variants [Preprint.] The study included 8,153 cases and their matched controls. Two-dose VE (95% confidence interval) was 86.7% (84.3-88.7%) against Delta infection, 98.4% (96.9-99.1%) against Alpha, 90.4% (73.9-96.5%) against Mu, 96-98% against other identified variants, and 79.9% (76.9-82.5%) against unidentified variants. VE against Delta declined from 94.1% (90.5-96.3%) 14-60 days after vaccination to 80.0% (70.2-86.6%) 151-180 days after vaccination. Waning was less pronounced for non-Delta variants. VE against Delta hospitalization was 97.6% (92.8-99.2%). Two doses of mRNA-1273 were highly effective against all SARS-CoV-2 variants. However, VE against Delta moderately declined with increasing time since vaccination.